| FAKE-08 | From-scratch PICO-8 cartridge player for unsupported homebrew consoles. | downloadable |
| FBZX | SDL/framebuffer ZX Spectrum emulator for Linux by Sergio Costas. | downloadable |
| FCEUX | Full-featured NES/Famicom emulator that merges the FCE Ultra family with extensive debugging and TAS tools. | downloadable |
| FM-7 | Fujitsu FM-7 emulator written in JavaScript, running its dual Motorola 6809 CPUs directly in a web browser. | online |
| FPse | Optimized commercial PlayStation emulator for mobile devices developed by Schtruck and LDChen. | downloadable |
| FS-UAE | Cross-platform Amiga emulator built on the WinUAE core, tuned for gaming. | downloadable |
| Fairchild Channel F | In-browser Fairchild Channel F emulator with a hand-written F8 core and a full debugger; boots the console's built-in Hockey and Tennis. | online |
| Fake86 | A portable open-source 8086/80186 IBM PC/XT emulator, later succeeded by XTulator. | downloadable |
| Felix | New-generation Atari Lynx emulator with advanced debugging features. | downloadable |
| Flycast | Actively maintained multiplatform Dreamcast, Naomi and Atomiswave emulator derived from reicast. | downloadable |
| Frodo | Free, portable Commodore 64 emulator by Christian Bauer focused on reproducing the C64's special graphics effects. | downloadable |
| Fujisan | Modern cross-platform Qt front-end for the Atari800 emulation core. | downloadable |
| Fuse | The Free Unix Spectrum Emulator, the standard ZX Spectrum emulator. | downloadable |
| fMSX | Veteran MSX/MSX2/MSX2+ emulator by Marat Fayzullin. | downloadable |